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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD1 All Species: 40.91
Human Site: S649 Identified Species: 75
UniProt: O14646 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14646 NP_001261.2 1710 196688 S649 T G T P L Q N S L K E L W S L
Chimpanzee Pan troglodytes XP_517850 1710 196736 S649 T G T P L Q N S L K E L W S L
Rhesus Macaque Macaca mulatta XP_001097125 1712 197047 S651 T G T P L Q N S L K E L W S L
Dog Lupus familis XP_848459 1711 196992 S648 T G T P L Q N S L K E L W S L
Cat Felis silvestris
Mouse Mus musculus P40201 1711 196392 S647 T G T P L Q N S L K E L W S L
Rat Rattus norvegicus Q9JIX5 2581 290674 T983 T G T P L Q N T V E E L F S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513135 1807 208022 S650 T G T P L Q N S L K E L W S L
Chicken Gallus gallus B6ZLK2 1719 197507 S645 T G T P L Q N S L K E L W S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 T1019 T G T P L Q N T V E E L F S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KU24 1883 211809 S696 T G T P L Q N S L K E L W A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 N798 T G T P L Q N N L E E L F H L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 N429 D E G H R L K N K D S K L F S
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 D513 K W Q F M A V D E A H R L K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 98.3 N.A. 95.7 23.3 N.A. 88.6 92.4 N.A. 23.6 N.A. 45.6 N.A. 26.3 N.A.
Protein Similarity: 100 99.8 99.8 99.3 N.A. 97.9 38.9 N.A. 91.6 95.9 N.A. 38.8 N.A. 62.1 N.A. 43.8 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 73.3 N.A. 100 100 N.A. 73.3 N.A. 93.3 N.A. 73.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 100 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 31.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 8 24 85 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 24 8 0 % F
% Gly: 0 85 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 8 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 8 0 8 62 0 8 0 8 0 % K
% Leu: 0 0 0 0 85 8 0 0 70 0 0 85 16 0 85 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 85 16 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 85 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 85 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 62 0 0 8 0 0 70 8 % S
% Thr: 85 0 85 0 0 0 0 16 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 16 0 0 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 62 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _